Successful non-invasive treatment of stricturing fibrosing colonopathy in an adult patient

Eur J Med Res. 2011 Sep 12;16(9):411-4. doi: 10.1186/2047-783x-16-9-411.


Objective: Fibrosing colonopathy (FC) is a rare entity associated with cystic fibrosis (CF). Until now, patients with stricturing FC have usually been treated surgically. In this instance, we aimed at avoiding surgery by applying a new conservative approach. -

Methods: Case report on an adult with CF who developed persistent abdominal pain due to a non-passable stricture in the right transverse colon. Histology confirmed fibrosing colonopathy. -

Results: Initially we treated the patient with prednisolone pulse therapy and additive antibiotic therapy. For maintenance therapy we administered budesonide. The patient underwent clinical, laboratory and endoscopic follow-up over a three-year period. The stricture healed and was easy to pass. A relapse in the cecum at the ileocecal valve again improved under steroid and antibiotic therapy. -

Conclusions: We present a novel therapeutic approach for advanced stricturing FC in an adult patient which successfully avoided surgery (right hemicolectomy) over a three year follow up.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Colon / pathology*
  • Colonic Diseases / drug therapy*
  • Colonic Diseases / etiology*
  • Cystic Fibrosis / complications*
  • Fibrosis / drug therapy*
  • Fibrosis / etiology*
  • Follow-Up Studies
  • Humans
  • Male
  • Time Factors
  • Treatment Outcome


  • Anti-Bacterial Agents