Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
, 33 (8), 790-5

Immunohistochemical Detection of Parvovirus B19 in "Gloves and Socks" Papular Purpuric Syndrome: Direct Evidence for Viral Endothelial Involvement. Report of Three Cases and Review of the Literature

Affiliations
Review

Immunohistochemical Detection of Parvovirus B19 in "Gloves and Socks" Papular Purpuric Syndrome: Direct Evidence for Viral Endothelial Involvement. Report of Three Cases and Review of the Literature

Carlos Santonja et al. Am J Dermatopathol.

Abstract

Papular-purpuric "gloves and socks" syndrome is a distinctive dermatosis featuring acral pruritus, edema, and petechiae. It has been attributed in most--but not all--reported cases to Parvovirus B19 infection, on the grounds of serological proof of recent infection or detection of viral DNA by polymerase chain reaction in patient serum or biopsies. We report the immunohistochemical detection of Parvovirus B19 VP2 structural protein in the endothelial lining of dermal blood vessels in 3 examples of Papular-purpuric "gloves and socks" syndrome and review previously described immunohistochemical investigations in cutaneous involvement by this infection.

Similar articles

See all similar articles

Cited by 2 articles

MeSH terms

LinkOut - more resources

Feedback