Left atrial appendage occlusion: lessons learned from surgical and transcatheter experiences

Ann Thorac Surg. 2011 Dec;92(6):2283-92. doi: 10.1016/j.athoracsur.2011.08.044. Epub 2011 Oct 25.


Since the 1950s, the pathophysiologic role of the left atrial appendage (LAA) has been known in thromboembolic disease. A variety of surgical techniques have been described to close the LAA, with various degrees of efficacy. Today, transcatheter devices for LAA occlusion may offer a less invasive solution. This review looks at the surgical experience with LAA occlusion, with a focus on the techniques of closure, the prospects for stroke reduction, and the percutaneous trials completed so far, to formulate some meaningful conclusions about the status of LAA closure today.

Publication types

  • Review

MeSH terms

  • Animals
  • Atrial Appendage / anatomy & histology
  • Atrial Appendage / physiology
  • Atrial Appendage / surgery*
  • Cardiac Catheterization
  • Echocardiography, Transesophageal
  • Humans
  • Stroke / prevention & control*