Heterozygous signal transducer and activator of transcription 3 mutations in hyper-IgE syndrome result in altered B-cell maturation

J Allergy Clin Immunol. 2012 Feb;129(2):559-62, 562.e1-2. doi: 10.1016/j.jaci.2011.09.017. Epub 2011 Oct 26.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • B-Cell Activating Factor / blood
  • B-Cell Activation Factor Receptor / immunology
  • B-Lymphocytes / cytology*
  • B-Lymphocytes / immunology
  • Bacteriophage phi X 174 / immunology*
  • Case-Control Studies
  • Cell Growth Processes
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Job Syndrome / blood
  • Job Syndrome / genetics
  • Job Syndrome / immunology*
  • Male
  • Middle Aged
  • Mutation
  • STAT3 Transcription Factor / genetics*
  • STAT3 Transcription Factor / metabolism
  • Signal Transduction
  • Young Adult

Substances

  • B-Cell Activating Factor
  • B-Cell Activation Factor Receptor
  • STAT3 Transcription Factor
  • TNFRSF13C protein, human
  • TNFSF13B protein, human