Crohn's disease and hyperbaric oxygen therapy

Acta Cir Bras. 2011:26 Suppl 2:129-32. doi: 10.1590/s0102-86502011000800024.


Purpose: Evaluate the application of Hyperbaric Oxygen Therapy (HBO) in patients with Crohn's disease (CD) refractory to pharmacologic therapy, who developed abdominal, anorectal or skin complications.

Methods: Fourteen selected patients with refractory CD and treated at the School of Medicine of Ribeirao Preto, University of Sao Paulo (FMRP-USP) and at the Center of Hyperbaric Medicine, São Paulo Hospital (CEMEHI) were submitted to HBO.

Results: Of the 14 patients evaluated, 11 had a satisfactory response.

Conclusion: HBO has shown benefits in patients with CD refractory to pharmacologic therapy.

MeSH terms

  • Adult
  • Combined Modality Therapy
  • Crohn Disease / therapy*
  • Humans
  • Hyperbaric Oxygenation / methods*
  • Middle Aged
  • Prospective Studies
  • Time Factors
  • Treatment Outcome
  • Young Adult