[Sterilization with ozone in health care: an integrative literature review]

Rev Esc Enferm USP. 2011 Oct;45(5):1243-9. doi: 10.1590/s0080-62342011000500030.
[Article in Portuguese]


The objective of this integrative literature review was to find evidence to support using ozone as a sterilizing agent for health products. The search was performed on the following bases: MEDLINE, SCOPUS, COCHRANE, COMPENDEX, INSPEC and ENGINEERING RESEARCH DATABASE; using ozone and sterilization as descriptors. Five articles were found between 1990 and 2008, which tested ozone as a sterilizer. All studies used the same type of investigation (experimental laboratory study) and achieved sterilization with ozone, but with different scopes and products, besides using different methodological procedures. Considering the ever-growing technology for new products, with the vast range of forms and materials, the findings point at ozone sterilization as a promising method, but still in an initial phase of investigation. Further experimental studies are needed to provide broader evidence regarding the possibilities and limitations of ozone sterilization.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Ozone*
  • Sterilization / methods*


  • Ozone