Accuracy of blind versus ultrasound-guided suprapatellar bursal injection

J Clin Ultrasound. 2012 Jan;40(1):20-5. doi: 10.1002/jcu.20890. Epub 2011 Oct 28.


Purpose: To compare the accuracy rates between ultrasound (US)-guided and blind knee intra-articular injection via the suprapatellar bursa.

Methods: Ninety-nine patients with radiographically confirmed knee osteoarthritis (Kellgren/Lawrence grade 2 or 3) without effusion were included. Fifty patients were assigned to the US-guided injection group and 49 to the blind injection group. After a US-guided or blind injection of hyaluronic acid (HA) and contrast dye through the suprapatellar bursa into the knee joint, a radiographic image was obtained in each case to ascertain whether all injected material had reached the intra-articular space.

Results: US-guided HA injection exhibited a significantly greater accuracy (48 of 50 knees, 96.0%) than blind injection (41 of 49 knees, 83.7%).

Conclusions: Intra-articular injections through the suprapatellar bursa under US guidance increased the accuracy of knee joint injections.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Bursa, Synovial
  • Female
  • Humans
  • Hyaluronic Acid / administration & dosage*
  • Hyaluronic Acid / therapeutic use
  • Injections, Intra-Articular / methods
  • Knee Joint / diagnostic imaging*
  • Male
  • Middle Aged
  • Osteoarthritis, Knee / diagnostic imaging
  • Osteoarthritis, Knee / drug therapy*
  • Prospective Studies
  • Radiography
  • Single-Blind Method
  • Ultrasonography, Interventional*
  • Viscosupplementation / methods*
  • Viscosupplements / administration & dosage*
  • Viscosupplements / therapeutic use


  • Viscosupplements
  • Hyaluronic Acid