East-Side story: the standardisation of psychotropic drugs at the Charité Psychiatric Clinic, 1955-1970

Stud Hist Philos Biol Biomed Sci. 2011 Dec;42(4):453-66. doi: 10.1016/j.shpsc.2011.06.001. Epub 2011 Jul 19.

Abstract

The present article illustrates the history of psychotropic drugs introduced in the German Democratic Republic (GDR) from 1945 onwards. We begin by examining the introduction of an anti-depressant and a tranquilizer at the university psychiatric clinic, Charité, in East Berlin. On the basis of patient files, we consider the monitoring routines, altered by the use of psychotropic drugs, and the difficulties that arose when these routines were translated into existing research programs. In the 1960s, attempts to evaluate the psychiatric practice were based on psychopathology whereas at the end of the 1960s there was a shift to "target symptoms".

Publication types

  • Historical Article

MeSH terms

  • Ambulatory Care Facilities / history*
  • Antidepressive Agents / history*
  • Antidepressive Agents / standards
  • Behavioral Symptoms / drug therapy
  • Behavioral Symptoms / history
  • Berlin
  • Biomedical Research / history*
  • Biomedical Research / methods
  • Evaluation Studies as Topic
  • Germany, East
  • History, 20th Century
  • Humans
  • Medical Records
  • Mental Disorders / complications
  • Mental Disorders / drug therapy
  • Mental Disorders / history*
  • Practice Patterns, Physicians' / history*
  • Psychiatry / history*
  • Psychiatry / methods
  • Psychopathology / history
  • Tranquilizing Agents / history*
  • Tranquilizing Agents / standards
  • Universities / history

Substances

  • Antidepressive Agents
  • Tranquilizing Agents