The value of growth hormone supplements in ART for poor ovarian responders

Fertil Steril. 2011 Nov;96(5):1069-76. doi: 10.1016/j.fertnstert.2011.09.049.


Recently, three meta-analyses have concluded that cotreatment with GH improves assisted reproduction outcome in poor controlled ovarian stimulation responders. Although generally GH supplements did not increase controlled ovarian stimulation response or number of oocytes, the supplements improved pregnancy and live-birth rates-thus speaking for an effect on oocyte quality.

Publication types

  • Review

MeSH terms

  • Drug Therapy, Combination
  • Evidence-Based Medicine
  • Female
  • Fertility Agents, Female / therapeutic use*
  • Growth Hormone / therapeutic use*
  • Humans
  • Infertility / physiopathology
  • Infertility / therapy*
  • Live Birth
  • Ovary / drug effects*
  • Ovary / physiopathology
  • Ovulation / drug effects*
  • Ovulation Induction / methods*
  • Patient Selection
  • Pregnancy
  • Pregnancy Rate
  • Treatment Failure


  • Fertility Agents, Female
  • Growth Hormone