Harry Belafonte and the Secret Proteome of Coconut Milk

J Proteomics. 2012 Jan 4;75(3):914-20. doi: 10.1016/j.jprot.2011.10.009. Epub 2011 Oct 20.


The proteome of coconut milk has been extensively mapped via capture at three pH values with combinatorial peptide ligand libraries (CPLL). A grand total of 307 unique gene products could be listed, 200 discovered via CPLL capture, 137 detected in the control, untreated material and 30 species in common between the two sets of data. This is by far the most extensive mapping of coconut milk, in which, up to the present, only a dozen proteins were known, those belonging to the high- to very-high abundance class. The database of coconut contains only 106 proteins: of those, only six are listed in our table. The vast majority of the classified proteins, thus, has been identified only by homologies with sequences deposited in the general viridiplantae database. This unique set of data could be the starting point for nutritionists and researchers involved in nutraceutics for enucleating some proteins responsible for some of the unique beneficial health effects attributed to coconut milk.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cocos / chemistry
  • Cocos / metabolism*
  • Databases, Protein*
  • Hydrogen-Ion Concentration
  • Nuts / chemistry
  • Nuts / metabolism*
  • Peptide Library
  • Plant Proteins, Dietary / analysis
  • Plant Proteins, Dietary / classification
  • Plant Proteins, Dietary / metabolism*
  • Proteome / analysis
  • Proteome / metabolism*


  • Peptide Library
  • Plant Proteins, Dietary
  • Proteome