Memory in paediatric temporal lobe epilepsy: effects of lesion type and side

Epilepsy Res. 2012 Feb;98(2-3):255-9. doi: 10.1016/j.eplepsyres.2011.09.004. Epub 2011 Oct 29.


This study investigated the role of underlying pathology on memory function of children with temporal lobe epilepsy (TLE). Memory was assessed in 44 children with TLE resulting from hippocampal sclerosis (HS) or dysembryoplastic neuroepithelial tumours (DNT), and 22 control children. Delayed story and paired associate recall performance was significantly more impaired in children with HS compared to those with DNT, irrespective of the affected side. Semantic memory was impaired in both HS groups, and also in the left DNT group. These results suggest a role for type, and to a lesser extent, side of pathology in the memory profile of children with TLE.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Association Learning
  • Brain Neoplasms / etiology
  • Child
  • Epilepsy, Temporal Lobe / complications*
  • Epilepsy, Temporal Lobe / etiology
  • Female
  • Hippocampus / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Memory Disorders / etiology*
  • Memory Disorders / pathology*
  • Mental Recall
  • Neuropsychological Tests
  • Sclerosis / etiology
  • Teratoma / etiology
  • Verbal Learning