A comparison of screening tools for the assessment of mild cognitive impairment: preliminary findings

Neurocase. 2012;18(4):336-51. doi: 10.1080/13554794.2011.608365. Epub 2011 Nov 2.


We report a pilot investigation into the utility of screening tools in Mild Cognitive Impairment (MCI). The Addenbrooke's Cognitive Examination-Revised (ACE-R), Montreal Cognitive Assessment (MoCA) and the novel Computer-Administered Neuropsychological Screen for Mild Cognitive Impairment (CANS-MCI) were administered to 20 elderly controls and 15 MCI cases. Non-parametric Mann-Whitney U-tests showed significant differences between groups (p < .0001) on the CANS-MCI and MoCA. The ACE-R and MoCA total scores showed high sensitivity (90%) to MCI. Area under the curve was consistently significant in discriminating controls and MCI for memory scores across all screening instruments. A useful profile of quantitative and qualitative information pertaining to cognitive functioning in MCI can be obtained with the MoCA, ACE-R, and CANS-MCI.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Area Under Curve
  • Cognitive Dysfunction / diagnosis*
  • Cognitive Dysfunction / psychology*
  • Cohort Studies
  • Educational Status
  • Female
  • Humans
  • Male
  • Memory
  • Mental Recall
  • Neuropsychological Tests*
  • Pilot Projects
  • ROC Curve
  • Reproducibility of Results