Lymphadenectomy for bladder cancer: indications and controversies

Urol Clin North Am. 2011 Nov;38(4):397-405, v. doi: 10.1016/j.ucl.2011.07.011.

Abstract

Pelvic lymph node dissection (PLND) at the time of cystectomy remains the most accurate method of staging and can have a positive impact on cancer control, and there is general agreement as to its necessity at the time of surgery. There is, however, a lack of consensus regarding the terminology of PLND and controversy concerning the optimal extent of lymph node dissection, especially because recent investigations have suggested a survival benefit with extended PLND.

Publication types

  • Review

MeSH terms

  • Biopsy, Needle
  • Carcinoma, Transitional Cell / mortality
  • Carcinoma, Transitional Cell / pathology
  • Carcinoma, Transitional Cell / surgery
  • Cystectomy / methods
  • Cystectomy / mortality
  • Humans
  • Immunohistochemistry
  • Lymph Node Excision / standards*
  • Lymph Node Excision / trends
  • Lymph Nodes / pathology*
  • Lymph Nodes / surgery
  • Male
  • Neoplasm Invasiveness
  • Neoplasm Recurrence, Local / mortality
  • Neoplasm Recurrence, Local / pathology*
  • Neoplasm Recurrence, Local / surgery
  • Neoplasm Staging
  • Pelvis / pathology
  • Pelvis / surgery
  • Prognosis
  • Risk Assessment
  • Survival Analysis
  • Urinary Bladder Neoplasms / mortality
  • Urinary Bladder Neoplasms / pathology*
  • Urinary Bladder Neoplasms / surgery*