[Myomectomy for infertile women: the role of surgery]

J Gynecol Obstet Biol Reprod (Paris). 2011 Dec;40(8):885-901. doi: 10.1016/j.jgyn.2011.09.014. Epub 2011 Nov 5.
[Article in French]

Abstract

At present, it is estimated that fibroids may be associated with infertility in 5 to 10% and are possibly the sole cause of infertility in 1 to 3%. Their effects on fertility remain debated. The aim of this review of published studies between January 1990 and November 2010 was to clarify the relation between myoma and fertility, and to assess the role of myomectomy in infertile patients. In assisted reproduction technology and spontaneous conception, hysteroscopic sub-mucous myoma resection increased pregnancy rates. Intramural fibroids appear to decrease fertility, but the myomectomy does not improve assisted reproduction technology and spontaneous fertility. More high-quality studies are needed to conclude toward the value of myomectomy for intramural fibroids. Subserosal fibroids do not affect fertility outcomes, and removal does not confer benefit.

Publication types

  • Evaluation Study
  • Review

MeSH terms

  • Female
  • Gynecologic Surgical Procedures / adverse effects
  • Gynecologic Surgical Procedures / methods
  • Gynecologic Surgical Procedures / statistics & numerical data*
  • Humans
  • Hysterectomy / adverse effects
  • Infertility, Female / complications
  • Infertility, Female / epidemiology
  • Infertility, Female / etiology
  • Infertility, Female / surgery*
  • Leiomyoma / complications
  • Leiomyoma / epidemiology
  • Leiomyoma / surgery*
  • Pregnancy
  • Pregnancy Complications, Neoplastic / epidemiology
  • Pregnancy Complications, Neoplastic / surgery
  • Pregnancy Rate
  • Reproductive Techniques, Assisted / statistics & numerical data
  • Uterine Neoplasms / complications
  • Uterine Neoplasms / epidemiology
  • Uterine Neoplasms / surgery*