Abstract
This review aims to highlight microwave-assisted organic synthesis as applied to medicinal chemistry in the last years, showing some reactions performed under microwave irradiation for the synthesis of distinct structurally molecules of biological interest, divided into the following groups: antineoplastics, anti-inflammatory, antimicrobial agents, antivirals, agents for the treatment of neglected diseases and central nervous system-acting prototypes.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Animals
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Anti-Infective Agents / chemical synthesis
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Anti-Infective Agents / chemistry
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Anti-Infective Agents / therapeutic use
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Anti-Inflammatory Agents / chemical synthesis
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Anti-Inflammatory Agents / chemistry
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Anti-Inflammatory Agents / therapeutic use
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Antineoplastic Agents / chemical synthesis
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / therapeutic use
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Antiviral Agents / chemical synthesis
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Antiviral Agents / chemistry
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Antiviral Agents / therapeutic use
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Central Nervous System Diseases / drug therapy
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Chemistry Techniques, Synthetic / methods*
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Chemistry, Pharmaceutical*
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Combinatorial Chemistry Techniques / methods*
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Heterocyclic Compounds / chemical synthesis
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Heterocyclic Compounds / chemistry
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Heterocyclic Compounds / therapeutic use
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Humans
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Microwaves*
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Molecular Structure
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Neglected Diseases / drug therapy
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Parasitic Diseases / drug therapy
Substances
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Anti-Infective Agents
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Anti-Inflammatory Agents
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Antineoplastic Agents
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Antiviral Agents
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Heterocyclic Compounds