Multiple intracranial mucoceles associated with phaeohyphomycosis of the paranasal sinuses

Arch Otolaryngol Head Neck Surg. 1990 Oct;116(10):1210-3. doi: 10.1001/archotol.1990.01870100104024.


The purpose of this article is to alert clinicians to a new pathogenic fungus of the paranasal sinuses called Exserohilum rostratum. Exserohilum species are one of the etiologic agents of phaeohyphomycosis, a constellation of entities caused by dematiaceous fungi. This class of fungal sinus infection has emerged only in the past decade; it occurs primarily in immunocompetent individuals and produces a tenacious, progressive pansinusitis. To our knowledge, this study describes the first case of multiple intracranial mucoceles secondary to E rostratum. The diagnostic workup includes computed tomography and magnetic resonance imaging followed by direct microscopic examination of tissue biopsy specimens. A craniotomy followed by a bilateral external ethmoidectomy was necessary for complete extirpation of the infected mucoceles. Aggressive surgical management of this mycotic infection is described.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Diseases / diagnostic imaging
  • Brain Diseases / etiology*
  • Brain Diseases / microbiology
  • Humans
  • Male
  • Mitosporic Fungi*
  • Mucocele / diagnostic imaging
  • Mucocele / etiology*
  • Mucocele / microbiology
  • Mycoses / complications*
  • Mycoses / diagnostic imaging
  • Sinusitis / complications*
  • Sinusitis / diagnostic imaging
  • Sinusitis / microbiology
  • Tomography, X-Ray Computed