Spontaneous remission of nephrotic syndrome in a patient with IgA nephropathy

Pediatr Nephrol. 1990 Jan;4(1):36-8. doi: 10.1007/BF00858435.


A patient with spontaneous remission of nephrotic syndrome (NS) associated with IgA nephropathy is described. The patient presented at the age of 8 years with asymptomatic proteinuria, and at the age of 11 years developed classical features of NS. A percutaneous renal biopsy showed mild mesangial prominence without significant hypercellularity, electron-dense deposits within the mesangium, and 3+ mesangial staining with IgA and IgG. NS resolved 6 weeks after onset without any form of therapy; absence of proteinuria persisted 6 months later. This report demonstrates clearly that patients with NS associated with IgA nephropathy may undergo spontaneous resolution of their proteinuria.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Child
  • Glomerular Mesangium / pathology
  • Glomerulonephritis, IGA / complications*
  • Glomerulonephritis, IGA / pathology
  • Humans
  • Male
  • Nephrotic Syndrome / complications
  • Nephrotic Syndrome / pathology
  • Nephrotic Syndrome / physiopathology*
  • Proteinuria / etiology
  • Remission, Spontaneous