On the futility of screening for genes that make you fat

PLoS Med. 2011 Nov;8(11):e1001114. doi: 10.1371/journal.pmed.1001114. Epub 2011 Nov 1.


J. Lennert Veerman discusses the implications for genetic screening of findings showing that physical activity substantially attenuates the effects of genetic variants which predispose towards obesity.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Alpha-Ketoglutarate-Dependent Dioxygenase FTO
  • Female
  • Genetic Predisposition to Disease*
  • Humans
  • Male
  • Motor Activity*
  • Obesity / genetics*
  • Polymorphism, Single Nucleotide*
  • Proteins / genetics*


  • Proteins
  • Alpha-Ketoglutarate-Dependent Dioxygenase FTO
  • FTO protein, human