Meiotic pairing as a polo match

Dev Cell. 2011 Nov 15;21(5):805-6. doi: 10.1016/j.devcel.2011.10.022.


In C. elegans, meiotic chromosome pairing is initiated by association of chromosomal sites known as pairing centers (PCs) with the nuclear periphery. The Dernburg and Zetka laboratories have shown that recruitment of Polo kinases to PCs at the nuclear envelope is essential to promote PC complex aggregation, pairing, and synapsis.

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