Emerging dynamics of human campylobacteriosis in Southern Ireland

FEMS Immunol Med Microbiol. 2011 Nov;63(2):248-53. doi: 10.1111/j.1574-695X.2011.00847.x.

Abstract

Infections with Campylobacter spp. pose a significant health burden worldwide. The significance of Campylobacter jejuni/Campylobacter coli infection is well appreciated but the contribution of non-C. jejuni/C. coli spp. to human gastroenteritis is largely unknown. In this study, we employed a two-tiered molecular study on 7194 patient faecal samples received by the Microbiology Department in Cork University Hospital during 2009. The first step, using EntericBio(®) (Serosep), a multiplex PCR system, detected Campylobacter to the genus level. The second step, utilizing Campylobacter species-specific PCR identified to the species level. A total of 340 samples were confirmed as Campylobacter genus positive, 329 of which were identified to species level with 33 samples containing mixed Campylobacter infections. Campylobacter jejuni, present in 72.4% of samples, was the most common species detected, however, 27.4% of patient samples contained non-C. jejuni/C. coli spp.; Campylobacter fetus (2.4%), Campylobacter upsaliensis (1.2%), Campylobacter hyointestinalis (1.5%), Campylobacter lari (0.6%) and an emerging species, Campylobacter ureolyticus (24.4%). We report a prominent seasonal distribution for campylobacteriosis (Spring), with C. ureolyticus (March) preceeding slightly C. jejuni/C. coli (April/May).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Bacteriological Techniques / methods
  • Campylobacter / classification*
  • Campylobacter / genetics
  • Campylobacter / isolation & purification*
  • Campylobacter Infections / epidemiology*
  • Campylobacter Infections / microbiology*
  • Child
  • Child, Preschool
  • Feces / microbiology
  • Female
  • Gastroenteritis / epidemiology*
  • Gastroenteritis / microbiology*
  • Humans
  • Ireland / epidemiology
  • Male
  • Middle Aged
  • Molecular Diagnostic Techniques / methods
  • Polymerase Chain Reaction / methods
  • Prevalence
  • Seasons
  • Young Adult