Self-administration of subcutaneous depot medroxyprogesterone acetate for contraception: feasibility and acceptability

Contraception. 2012 May;85(5):453-7. doi: 10.1016/j.contraception.2011.09.015. Epub 2011 Nov 12.

Abstract

Background: The objectives of the study were to assess feasibility, continuation rates and patient satisfaction with self-administration of subcutaneous depot medroxyprogesterone acetate (DMPA-SC).

Materials and methods: The study included 50 DMPA-seeking women between the ages of 18 and 49 years enrolled at two Florida Planned Parenthood health centers. Participants were taught self-injection during their initial study visit and, upon proficiency, self-injected one dose in clinic. Participants then injected a series of three more doses outside the health center over 9 months. Continuation rates, feasibility and acceptability were determined by analysis of four postinjection surveys.

Results: Continuation of DMPA-SC at injection 4 was 74% (95% confidence interval 62%-86%). Overall, survey responses from the three at-home injections indicated the method to be convenient (95%), easy (87%) and recommendable to others (94%). Twenty percent of injections were met with difficulty, most commonly cited as plunger resistance. No pregnancies occurred in study.

Conclusions: Continuation was high with DMPA-SC self-injection. Participants reported injection to be easy and convenient and are likely to recommend self-administration to other women. Device issues are one potential deterrent.

Publication types

  • Clinical Trial
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Contraceptive Agents, Female / administration & dosage*
  • Contraceptive Agents, Female / adverse effects
  • Delayed-Action Preparations / administration & dosage
  • Delayed-Action Preparations / adverse effects
  • Family Planning Services
  • Feasibility Studies
  • Female
  • Florida
  • Humans
  • Injections, Subcutaneous
  • Medroxyprogesterone Acetate / administration & dosage*
  • Medroxyprogesterone Acetate / adverse effects
  • Middle Aged
  • Patient Dropouts
  • Patient Education as Topic
  • Patient Satisfaction*
  • Prospective Studies
  • Self Administration
  • Surveys and Questionnaires
  • Voluntary Health Agencies
  • Young Adult

Substances

  • Contraceptive Agents, Female
  • Delayed-Action Preparations
  • Medroxyprogesterone Acetate