Stent-assisted aneurysm coil embolization: safety and efficacy at a low-volume center

Neurol Res. 2011 Nov;33(9):942-6. doi: 10.1179/1743132811Y.0000000014.


Background and purpose: To compare safety and efficacy of cerebral aneurysm embolization with and without Neuroform stent placement at a low procedural volume center.

Methods: Retrospective cohort study of unruptured aneurysm coil embolization with and without Neuroform stent assistance over a period of 53 months at a center performing 14.4 interventions per year. Neuroform stent-assisted embolization was performed for 26 aneurysms in 25 patients (mean age: 61.3 years). Twelve patients (mean age: 64.3 years) with 12 unruptured aneurysms were treated without stent support. Comparative analysis of complications, angiographic findings, and clinical outcomes was performed.

Results: Procedural complications for the Neuroform stent group was 7.69% (2/26) versus 8.34% (1/12) for aneurysms without (P=0.7; OR: 1.1; CI: 0.09-13.35).The Modified Rankin Scale (MRS) and Glasgow Outcome Scale (GOS) scores for all patients in the stent and non-stent groups were 0 and 5, respectively. Three out of 20 aneurysms (15%) were retreated for major recurrence in the stent group and two of 10 (20%) in the non-stent group (P=0.55; OR: 1.42; 95% CI: 0.20-10.23). At a mean follow-up of 16.9 months, persistent complete occlusion was observed in 36.8% (7/19) of aneurysms with stent support. At a mean of 15.9-month follow-up in 10 non-stented aneurysms, persistent complete occlusion was observed in 50% of aneurysms (P=0.69; OR=2.3; 95% CI: 0.38-14.2).

Conclusion: Neuroform stent-assisted coil embolization at a low volume center is efficacious and does not increase procedural risk with optimal operator experience.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cerebral Angiography
  • Embolization, Therapeutic / adverse effects
  • Embolization, Therapeutic / instrumentation*
  • Female
  • Humans
  • Intracranial Aneurysm / therapy*
  • Male
  • Middle Aged
  • Stents* / adverse effects