Using Cluster Heat Maps to Investigate Relationships Between Body Composition and Laboratory Measurements in HIV-infected and HIV-uninfected Children and Young Adults

J Acquir Immune Defic Syndr. 2012 Mar 1;59(3):325-8. doi: 10.1097/QAI.0b013e31823fdbec.

Abstract

Cluster heat maps were used to investigate relationships between body composition, lipid levels, and glucose metabolism in HIV-infected and HIV-uninfected children and young adults using data from a cross-sectional study. Three distinct clusters of participants were identified. One group had lower body fat and higher lipid measures and was mostly HIV infected. The other 2 groups were a mix of HIV-infected and HIV-uninfected participants. Of these, 1 cluster had more participants with higher body fat and insulin resistance, which are risk factors for future cardiovascular disease, and the other had relatively normal measurements on all outcomes.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Absorptiometry, Photon
  • Adolescent
  • Blood Glucose / metabolism*
  • Body Composition / physiology*
  • Child
  • Cluster Analysis
  • Cross-Sectional Studies
  • Female
  • HIV / isolation & purification*
  • HIV Infections / metabolism*
  • Humans
  • Lipid Metabolism / physiology*
  • Logistic Models
  • Male
  • Young Adult

Substances

  • Blood Glucose