Variant angina due to deficiency of intracellular magnesium

Clin Cardiol. 1990 Sep;13(9):663-5. doi: 10.1002/clc.4960130914.


A 51-year-old man was diagnosed as having variant angina by documentation of typical ST elevation during anginal attack and also by showing coronary arterial spasm (#2 and #12) during hyperventilation on coronary arteriography. Large quantities of calcium blocking agents and nitrates could not improve his symptoms. Lack of intracellular magnesium was suspected from a daily excretion of urine magnesium (5.3 mEq) and magnesium tolerance test (56.7%). After hourly infusion of magnesium sulfate (80 mEq), coronary spasm could not be induced by ergonovine.

Publication types

  • Case Reports

MeSH terms

  • Angina Pectoris, Variant / etiology*
  • Coronary Vasospasm / etiology
  • Electrocardiography
  • Humans
  • Magnesium / urine
  • Magnesium Deficiency / complications*
  • Magnesium Deficiency / urine
  • Male
  • Middle Aged


  • Magnesium