Adherence and motility characteristics of clinical Acinetobacter baumannii isolates

FEMS Microbiol Lett. 2011 Oct;323(1):44-51. doi: 10.1111/j.1574-6968.2011.02362.x. Epub 2011 Aug 9.


Acinetobacter baumannii continues to be a major health problem especially in hospital settings. Herein, features that may play a role in persistence and disease potential were investigated in a collection of clinical A. baumannii strains from Australia. Twitching motility was found to be a common trait in A. baumannii international clone I strains and in abundant biofilm formers, whereas swarming motility was only observed in isolates not classified within the international clone lineages. Bioinformatic analysis of the type IV fimbriae revealed a correlation between PilA sequence homology and motility. A high level of variability in adherence to both abiotic surfaces and epithelial cells was found. We report for the first time the motility characteristics of a large number of A. baumannii isolates and present a direct comparison of A. baumannii binding to nasopharyngeal and lung epithelial cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter Infections / microbiology*
  • Acinetobacter baumannii / isolation & purification
  • Acinetobacter baumannii / pathogenicity*
  • Acinetobacter baumannii / physiology*
  • Australia
  • Bacterial Adhesion*
  • Computational Biology
  • Epithelial Cells / microbiology
  • Fimbriae Proteins / genetics
  • Humans
  • Locomotion*


  • Fimbriae Proteins