Artificial sweetener use among children: epidemiology, recommendations, metabolic outcomes, and future directions

Pediatr Clin North Am. 2011 Dec;58(6):1467-80, xi. doi: 10.1016/j.pcl.2011.09.007. Epub 2011 Oct 14.


This review summarizes the literature pertaining to the epidemiology and current recommendations for pediatric artificial sweetener use and presents the results of studies investigating metabolic responses to artificial sweeteners among children. An understanding of the research previously conducted and the gaps that remain will inform future clinical and translational research, to develop evidence-based recommendations for artificial sweetener use in the prevention and treatment of pediatric obesity.

Publication types

  • Research Support, N.I.H., Intramural
  • Review

MeSH terms

  • Adolescent
  • Behavior, Addictive / chemically induced
  • Blood Glucose / drug effects
  • Child
  • Child, Preschool
  • Humans
  • Obesity / prevention & control*
  • Sweetening Agents / adverse effects
  • Sweetening Agents / pharmacology*
  • Taste / drug effects
  • Weight Gain / drug effects


  • Blood Glucose
  • Sweetening Agents