Trauma and work-related pain syndromes: risk factors, clinical picture, insurance and law interventions

Best Pract Res Clin Rheumatol. 2011 Apr;25(2):199-207. doi: 10.1016/j.berh.2011.01.003.


In the past decade, major progress has been made in our understanding of fibromyalgia syndrome (FMS). Various triggers have been implicated as contributing to symptom development in FMS when genetically susceptible individuals are challenged. A substantial amount of data points towards the association between trauma and chronic widespread pain/fibromyalgia syndrome (CWP/FMS). There is abundant data suggesting that the pathogenesis of CWP/FMS might be related to cervical spine injury. Furthermore, several persistent local pain conditions may progress to CWP/FMS. These conditions may share a common pathogenic mechanism namely, central sensitisation. Physical trauma and emotional trauma co-exist in many traumatic events and may interact in the pathogenesis of CWP/FMS.

Publication types

  • Review

MeSH terms

  • Accidents, Occupational / legislation & jurisprudence*
  • Central Nervous System Sensitization / physiology
  • Cervical Vertebrae / injuries
  • Chronic Pain / epidemiology
  • Chronic Pain / etiology*
  • Chronic Pain / physiopathology
  • Disability Evaluation
  • Fibromyalgia / epidemiology
  • Fibromyalgia / etiology*
  • Fibromyalgia / physiopathology
  • Humans
  • Insurance, Health, Reimbursement
  • Occupational Diseases / epidemiology
  • Occupational Diseases / etiology*
  • Occupational Diseases / physiopathology
  • Risk Factors
  • Spinal Injuries / epidemiology
  • Spinal Injuries / etiology
  • Spinal Injuries / physiopathology
  • Syndrome
  • Wounds and Injuries / complications*
  • Wounds and Injuries / epidemiology
  • Wounds and Injuries / physiopathology