Iron overload: what is the role of public health?

Am J Prev Med. 2011 Dec;41(6 Suppl 4):S422-7. doi: 10.1016/j.amepre.2011.09.020.


Hereditary hemochromatosis type 1, also known as hereditary hemochromatosis classical (HHC), is an iron overload disorder associated, in most cases, with mutations of the hemochromatosis (HFE) gene. Although suggested algorithms for diagnosing iron overload are available, there are still questions about options for genetic and biochemical screening for hemochromatosis and duration of treatment. This article provides a summary of an expert workgroup meeting convened on September 24-25, 2009, entitled "Iron Overload: What is the Role of Public Health?" The purpose of the meeting was to enable subject matter experts to share their most recent clinical and scientific iron overload information and to facilitate the discussion of future endeavors, with special emphasis on the role of public health in this field. The two main topics were the research priorities of the field, including clinical, genetic, and public health issues, and the concerns about the validity of current screening recommendations for the condition.

Publication types

  • Congress

MeSH terms

  • Humans
  • Iron Overload* / diagnosis
  • Iron Overload* / drug therapy
  • Iron Overload* / genetics
  • Mass Screening / methods
  • Public Health Practice*
  • Research