Pulmonary, rhino-orbital and cutaneous mucormycosis caused by Rhizomucor pusillus in an immunocompromised patient

Clin Exp Dermatol. 2012 Jun;37(4):355-7. doi: 10.1111/j.1365-2230.2011.04235.x. Epub 2011 Nov 21.


The number of patients with haematopoietic malignancies receiving chemotherapy and stem-cell transplantation has increased the incidence of severe opportunistic infections. Systemic fungal infections are of major concern in immunocompromised patients, as these infections are often fatal. We report a case of a patient with acute myeloid leukaemia who developed multiple cutaneous plaques and necrotizing infiltrates in the lungs during chemotherapy. Using real-time PCR on a wax-embedded tissue sample, Rhizomucor pusillus was identified. We provide an overview of the literature on cutaneous mucormycosis and its diagnosis by PCR.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Aged
  • Dermatomycoses / microbiology*
  • Humans
  • Immunocompromised Host*
  • Lung Diseases, Fungal / microbiology*
  • Male
  • Mucormycosis / microbiology*
  • Polymerase Chain Reaction
  • Rhizomucor / isolation & purification*
  • Sinusitis / microbiology*