Ethyl glucuronide

Ann Clin Biochem. 2012 Mar;49(Pt 2):110-7. doi: 10.1258/acb.2011.011115. Epub 2011 Nov 23.

Abstract

Alcohol is associated with significant morbidity and mortality. Subjects abusing alcohol can be identified through clinical history, examination or self-report questionnaires. A range of biomarkers is available for detecting alcohol misuse, but there is still a need for a marker that can detect alcohol consumption in the time window between one day (ethanol) and one week (gamma-glutamyl transpeptidase and carbohydrate-deficient transferrin). Ethyl glucuronide is a direct metabolite that can be detected in urine for up to 90 h and has the potential to become a useful marker of 'binge' drinking. As a non-invasive marker, it could have a role in a variety of clinical and forensic settings.

Publication types

  • Review

MeSH terms

  • Biomarkers / urine*
  • Chromatography, Liquid
  • Glucuronates / urine*
  • Humans
  • Tandem Mass Spectrometry

Substances

  • Biomarkers
  • Glucuronates
  • ethyl glucuronide