Growth and hormonal response of intact and castrate male cattle to trenbolone acetate and estradiol

J Anim Sci. 1990 Sep;68(9):2682-9. doi: 10.2527/1990.6892682x.


Effects of castration and anabolic implants on weight gain, rib soft tissue composition and serum hormones were studied in cattle using a completely random design with a 2 x 2 factorial arrangement. Half of 16 bulls and 16 steers (Angus or Angus x Brahman) aged 9 mo and weighing 290 kg were treated with an implant (200 mg trenbolone acetate and 24 mg estradiol). Half of each group were not treated with an implant. A growing diet was fed for 95 d and half the animals in each group were slaughtered. Animals in the treated groups were reimplanted with trenbolone acetate and fed a finishing diet for 84 d and slaughtered. Percentage dry matter, fat and protein were determined on soft tissue from the 9-10-11th rib. Two blood samples were collected from each animal every 2 wk. Serum was assayed for five hormones. During the growing phase, untreated and treated bulls and treated steers gained more weight and had leaner rib sections that untreated steers (P less than .05); after the finishing phase, there were no differences among groups. Untreated steers had lower insulin-like growth factor (IGF-I) and higher cortisol concentrations during both phases of growth than untreated bulls did (P less than .05). Treatment with implants increased IGF-I concentrations in steers during both phases and reduced cortisol during the finishing phase.(ABSTRACT TRUNCATED AT 250 WORDS)

MeSH terms

  • Anabolic Agents / administration & dosage
  • Anabolic Agents / blood
  • Anabolic Agents / pharmacology*
  • Animals
  • Body Composition / drug effects
  • Cattle / growth & development*
  • Cattle / metabolism
  • Dose-Response Relationship, Drug
  • Drug Implants
  • Estradiol / administration & dosage
  • Estradiol / blood
  • Estradiol / pharmacology*
  • Hydrocortisone / blood
  • Insulin-Like Growth Factor I / analysis
  • Male
  • Orchiectomy / veterinary*
  • Testosterone / blood
  • Trenbolone Acetate / administration & dosage
  • Trenbolone Acetate / analogs & derivatives*
  • Trenbolone Acetate / blood
  • Trenbolone Acetate / pharmacology
  • Weight Gain / drug effects


  • Anabolic Agents
  • Drug Implants
  • Testosterone
  • Estradiol
  • Insulin-Like Growth Factor I
  • Trenbolone Acetate
  • Hydrocortisone