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, 1 (4), 210-3

Remineralization of Early Enamel Lesions Using Casein Phosphopeptide Amorphous Calcium Phosphate: An Ex-Vivo Study

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Remineralization of Early Enamel Lesions Using Casein Phosphopeptide Amorphous Calcium Phosphate: An Ex-Vivo Study

Ruchi Vashisht et al. Contemp Clin Dent.

Abstract

Objective: This study aimed at qualitatively evaluating the remineralization potential of casein phosphopeptide amorphous calcium phosphate on artificial early enamel lesions in an ex-vivo scenario by observing the treated tooth surface using a scanning electron microscope (SEM).

Materials and methods: This randomized study was conducted on 10 subjects undergoing orthodontic treatment with premolar extraction as part of their treatment. Artificial white lesions were created with the application of 37% phosphoric acid for 20 mins. Teeth were then divided into two groups: one experimental and the other control. Customised orthodontic band with a window was luted with intermediate restorative material in the experimental group whereas in the control group, band without a window was luted. The casein phosphopeptide amorphous calcium phosphate (GC TOOTH MOUSSE) paste was then applied on the window region of the experimental group for 3 mins thrice daily after meals for 14 days, whereas no paste was applied in the control group. After 14 days, teeth were extracted and viewed under an SEM.

Results: The study groups showed remineralization of the lesions as compared with the control group in most of the samples.

Conclusion: Casein phophopeptide could significantly remineralize the artificial enamel lesions in vivo.

Keywords: Enamel remineralisation; casein-phosphopeptide amorphous calcium phosphate.

Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Acid etching performed for 20 min on 14 and 44
Figure 2
Figure 2
Upper premolar (14)-:experimental group; lower premolar (44)-:control group
Figure 3
Figure 3
Application of GC TOOTH MOUSSE paste in the experimental-group(tooth-14)
Figure 4a
Figure 4a
Case1-control group (shows the demineralised enamel surface)
Figure 4b
Figure 4b
Case1-experimental-group (mineral phase deposited after application of CPP-ACP paste)
Figure 5a
Figure 5a
Case 2-control group (demineralised surface)
Figure 5b
Figure 5b
Case 2-Experimental group (after application of CPP-ACP paste)

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