Primary T-cell lymphoma of the urinary bladder presenting with haematuria and hydroureteronephrosis

J Int Med Res. 2011;39(5):2027-32. doi: 10.1177/147323001103900550.


Primary bladder lymphoma, a rare form of non-Hodgkin's lymphoma that is confined to the urinary bladder, is usually of B-cell origin. This report describes an extremely rare case of primary T-cell lymphoma of the urinary bladder. A 45-year-old man presented with haematuria, dysuria and loin pain. Ultrasonography and computed tomography showed a thickened left bladder wall and left hydroureteronephrosis. A diagnosis of primary T-cell lymphoma of the urinary bladder was made on the basis of clinical, radiological and histological findings. The patient, following transurethral resection, was treated with four cycles of CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) chemotherapy with a good response and remains in clinical remission 12 months after treatment.

Publication types

  • Case Reports

MeSH terms

  • Disease-Free Survival
  • Gene Rearrangement
  • Genes, T-Cell Receptor gamma
  • Hematuria / etiology*
  • Humans
  • Hydronephrosis / etiology*
  • Lymphoma, T-Cell / complications
  • Lymphoma, T-Cell / diagnostic imaging*
  • Lymphoma, T-Cell / genetics
  • Lymphoma, T-Cell / therapy
  • Male
  • Middle Aged
  • Radiography
  • Ureteral Diseases / etiology*
  • Urinary Bladder Neoplasms / complications
  • Urinary Bladder Neoplasms / diagnostic imaging*
  • Urinary Bladder Neoplasms / genetics
  • Urinary Bladder Neoplasms / therapy