Synthetic and green vegetable isothiocyanates target red blood leukemia cancers

Anjali Prashar; Faraha Siddiqui; Amit Kumar Singh

doi:10.1016/j.fitote.2011.11.012

Synthetic and green vegetable isothiocyanates target red blood leukemia cancers

Fitoterapia. 2012 Mar;83(2):255-65. doi: 10.1016/j.fitote.2011.11.012. Epub 2011 Nov 20.

Authors

Anjali Prashar¹, Faraha Siddiqui, Amit Kumar Singh

Affiliation

¹ Lifezone Biotech Private Limited, B-102, Phase III, KSSIDC, Electronic City, Bangalore, India. dr_anjaliprashar@hotmail.com

PMID: 22120500
DOI: 10.1016/j.fitote.2011.11.012

Abstract

Isothiocyanates (ITCs), the breakdown products of glucosinolates found primarily in species of Brassicaceae (Cruciferae), are potential anti-cancer compounds. This review compiles data on how through different modes of action ITCs and their synthetic counterparts target leukemia.

Publication types

Review

MeSH terms

Antineoplastic Agents / pharmacology*
Apoptosis / drug effects
Brassicaceae / chemistry*
Cell Survival / drug effects
Glucosinolates / metabolism*
Humans
Isothiocyanates / pharmacology
Leukemia / drug therapy*

Substances

Antineoplastic Agents
Glucosinolates
Isothiocyanates