Pathogenesis and prevention of type 2 diabetes: parental determinants, breastfeeding, and early childhood nutrition

Curr Diab Rep. 2012 Feb;12(1):82-7. doi: 10.1007/s11892-011-0246-3.


Among the factors predisposing to type 2 diabetes in children, adolescents, and young adults, the health and behavior of both the mother and father are critical. Prevention and treatment of parental nutritional disorders (including obesity and malnutrition), promotion of breastfeeding, and avoidance of overfeeding of young children are essential for childhood health and metabolic function. Focusing research and policy on parental influences on childhood health should reduce the risks of obesity and type 2 diabetes in future generations.

Publication types

  • Review

MeSH terms

  • Adult
  • Breast Feeding*
  • Child
  • Child Nutritional Physiological Phenomena
  • Child of Impaired Parents*
  • Child, Preschool
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / prevention & control*
  • Female
  • Health Promotion
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Malnutrition / epidemiology
  • Malnutrition / prevention & control*
  • Maternal Nutritional Physiological Phenomena
  • Obesity / epidemiology
  • Obesity / prevention & control*
  • Parents*
  • Pregnancy