Combined process automation for large-scale EEG analysis

Comput Biol Med. 2012 Jan;42(1):129-34. doi: 10.1016/j.compbiomed.2011.10.017. Epub 2011 Nov 30.


Epileptogenesis is a dynamic process producing increased seizure susceptibility. Electroencephalography (EEG) data provides information critical in understanding the evolution of epileptiform changes throughout epileptic foci. We designed an algorithm to facilitate efficient large-scale EEG analysis via linked automation of multiple data processing steps. Using EEG recordings obtained from electrical stimulation studies, the following steps of EEG analysis were automated: (1) alignment and isolation of pre- and post-stimulation intervals, (2) generation of user-defined band frequency waveforms, (3) spike-sorting, (4) quantification of spike and burst data and (5) power spectral density analysis. This algorithm allows for quicker, more efficient EEG analysis.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Algorithms
  • Animals
  • Deep Brain Stimulation
  • Electroencephalography / methods*
  • Male
  • Rats
  • Rats, Wistar
  • Seizures / physiopathology*
  • Signal Processing, Computer-Assisted*