A randomized controlled trial comparing 2 interventions for visual field loss with standard occupational therapy during inpatient stroke rehabilitation

Neurorehabil Neural Repair. 2012 Jun;26(5):463-9. doi: 10.1177/1545968311425927. Epub 2011 Dec 2.


Background and purpose: Compensatory and restorative treatments have been developed to improve visual field defects after stroke. However, no controlled trials have compared these interventions with standard occupational therapy (OT).

Methods: A total of 45 stroke participants with visual field defect admitted for inpatient rehabilitation were randomized to restorative computerized training (RT) using computer-based stimulation of border areas of their visual field defects or to a computer-based compensatory therapy (CT) teaching a visual search strategy. OT, in which different compensation strategies were used to train for activities of daily living, served as standard treatment for the active control group. Each treatment group received 15 single sessions of 30 minutes distributed over 3 weeks. The primary outcome measures were visual field expansion for RT, visual search performance for CT, and reading performance for both treatments. Visual conjunction search, alertness, and the Barthel Index were secondary outcomes.

Results: Compared with OT, CT resulted in a better visual search performance, and RT did not result in a larger expansion of the visual field. Intragroup pre-post comparisons demonstrated that CT improved all defined outcome parameters and RT several, whereas OT only improved one.

Conclusions: CT improved functional deficits after visual field loss compared with standard OT and may be the intervention of choice during inpatient rehabilitation. A larger trial that includes lesion location in the analysis is recommended.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Activities of Daily Living
  • Adaptation, Physiological
  • Adult
  • Aged
  • Attention
  • Computer-Assisted Instruction / methods
  • Female
  • Follow-Up Studies
  • Functional Laterality
  • Humans
  • Male
  • Middle Aged
  • Occupational Therapy / methods*
  • Perceptual Disorders / etiology*
  • Perceptual Disorders / rehabilitation*
  • Photic Stimulation
  • Physical Therapy Modalities*
  • Reading
  • Stroke / complications*
  • Stroke Rehabilitation
  • Treatment Outcome
  • Visual Fields / physiology*