Glycemic control in Iranian children with type 1 diabetes mellitus: effect of gender

Indian J Pediatr. 2012 Jul;79(7):896-900. doi: 10.1007/s12098-011-0613-8. Epub 2011 Dec 3.


Objectives: To evaluate the effect of gender on glycemic control, diabetic complications and associated abnormalities in patients with type 1 diabetes mellitus (T1DM).

Methods: In the present cross-sectional study, patients with T1DM referred to endocrinology clinic in children's hospital medical center in Tehran from March 2005 through March 2007 were enrolled. For each patient a questionnaire was filled. Finally, effect of gender on glycemic control was analyzed.

Results: Male patients did self monitoring of blood glucose significantly more than female patients. Mean HbA1c which is used as an indicator of glycemic control, insulin dose per kg of body weight and also frequency of diabetic ketoacidosis (DKA), height problems and dyslipidemia were significantly higher in female patients.

Conclusions: Because of worse glycemic control and higher incidence of DKA, dyslipidemia and height problems in female patients, focus on glycemic control of female patients according to local guidelines on clinical management of T1DM is required.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Biomarkers / blood
  • Blood Glucose / analysis
  • Blood Glucose / metabolism*
  • Blood Glucose Self-Monitoring / statistics & numerical data
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 1 / blood*
  • Diabetes Mellitus, Type 1 / complications
  • Diabetes Mellitus, Type 1 / drug therapy
  • Diabetic Ketoacidosis / etiology
  • Dyslipidemias / etiology
  • Female
  • Glycated Hemoglobin A / metabolism*
  • Growth Disorders / etiology
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Insulin / therapeutic use
  • Iran
  • Male
  • Sex Factors
  • Surveys and Questionnaires


  • Biomarkers
  • Blood Glucose
  • Glycated Hemoglobin A
  • Hypoglycemic Agents
  • Insulin
  • hemoglobin A1c protein, human