Cancer cachexia

J Oral Maxillofac Pathol. 2011 Sep;15(3):257-60. doi: 10.4103/0973-029X.86670.


Cancer cachexia is a wasting syndrome characterized by weight loss, anorexia, asthenia and anemia. The pathogenicity of this syndrome is multifactorial, due to a complex interaction of tumor and host factors. The signs and symptoms of cachexia are considered as the prognostic parameters in cancer patients. This review gives an emphasis on the various mechanisms involved in cachexia and an insight into head and neck cancer cachexia.

Keywords: Cachexia; head and neck cancer; tissue wasting; wasting syndrome.