Optical tweezers study life under tension

Nat Photonics. 2011 May 31;5:318-321. doi: 10.1038/nphoton.2011.100.


Optical tweezers have become one of the primary weapons in the arsenal of biophysicists, and have revolutionized the new field of single-molecule biophysics. Today's techniques allow high-resolution experiments on biological macromolecules that were mere pipe dreams only a decade ago.