Neuro-endocrine regulation of blood pressure

Indian J Endocrinol Metab. 2011 Oct;15 Suppl 4(Suppl4):S281-8. doi: 10.4103/2230-8210.86860.


As our understanding of the underlying aetiology of hypertension is far from adequate, over 90% of patients with hypertension receive a diagnosis of essential hypertension. This non-specific diagnosis leads to suboptimal therapeutics and a major problem with non-compliance. Understanding the normal control of blood pressure (BP) is, hence, important for a better understanding of the disease.This review attempts to unravel the present understanding of BP control. The local mechanisms of BP control, the neural mechanisms, renal-endocrine mechanisms, and a variety of other hormones that have a bearing in normal BP control are discussed and the possible role in the pathophysiology is alluded to.

Keywords: Blood pressure; neural control; renin-angiotensin-aldosterone system.