Clinical efficacy of facial masks containing yoghurt and Opuntia humifusa Raf. (F-YOP)

J Cosmet Sci. 2011 Sep-Oct;62(5):505-14.


Facial packs or masks are popular beauty treatments that are thought to improve skin quality. We formulated a yoghurt pack using natural ingredients (F-YOP), with consideration of skin affinity, safety, health, and beauty. Then, we performed an in vitro assessment of biological activity and in vivo assessments of moisture, TEWL, melanin content, and elasticity. Facial areas treated with F-YOP showed increased moisture compared to control regions: 89±6.26% (forehead), 140.72±10.19% (cheek), and 123.29±6.67% (chin). Transepidermal water loss (TEWL) values were decreased in the treated areas compared to control: 101.38±6.95% (forehead), 50.37±5.93% (cheek), and l57.81±10.88% (chin). Elasticity was decreased in the control region, whereas the treatment region did not change. The initial elasticity was maintained in the cheek. F-YOP exhibited activity on DPPH radical scavenging, SOD-like activity, and lipoxygenase activity. F-YOP treatment successfully improved the moisture, brightness, and elasticity of treated skin.

Publication types

  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cosmetics / chemistry
  • Cosmetics / pharmacology*
  • Elasticity / drug effects
  • Elasticity / physiology
  • Face
  • Female
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / pharmacology
  • Humans
  • Male
  • Melanins / analysis
  • Opuntia*
  • Phytotherapy*
  • Plant Preparations / chemistry
  • Plant Preparations / pharmacology*
  • Skin / chemistry
  • Skin / drug effects*
  • Skin Aging / drug effects
  • Skin Physiological Phenomena / drug effects
  • Water Loss, Insensible / drug effects
  • Water Loss, Insensible / physiology
  • Yogurt*


  • Cosmetics
  • Free Radical Scavengers
  • Melanins
  • Plant Preparations