Lenticular meridional astigmatism secondary to iris mesectodermal leiomyoma

J Cataract Refract Surg. 2012 Jan;38(1):170-3. doi: 10.1016/j.jcrs.2011.10.016.


A 61-year-old African American man presented with decreased vision of 2 months duration. Examination revealed a significant lenticular astigmatism and sectoral cataract as a result of an amelanotic iris lesion. Slitlamp optical coherence tomography (OCT) revealed angle crowding. An excisional biopsy was performed along with phacoemulsification in the right eye, with intraocular lens implantation for meridional lenticular astigmatism. Histopathology and histoimmunochemistry confirmed a diagnosis of uveal mesectodermal leiomyoma. Lenticular astigmatism may be a subtle sign of an anterior segment tumor. Anterior segment slitlamp OCT is an effective tool in diagnosing as well as monitoring small interval changes in these types of tumors.

Publication types

  • Case Reports

MeSH terms

  • Astigmatism / etiology*
  • Biomarkers, Tumor / analysis
  • Fluorescein Angiography
  • Humans
  • Iris Neoplasms / chemistry
  • Iris Neoplasms / complications*
  • Iris Neoplasms / diagnosis
  • Leiomyoma / chemistry
  • Leiomyoma / complications*
  • Leiomyoma / diagnosis
  • Lens Diseases / etiology*
  • Male
  • Middle Aged
  • Tomography, Optical Coherence
  • Vision Disorders / etiology
  • Visual Acuity


  • Biomarkers, Tumor