Impact of Genetic Background on Placental Glycogen Storage in Mice

Placenta. 2012 Feb;33(2):124-7. doi: 10.1016/j.placenta.2011.11.011. Epub 2011 Dec 7.

Abstract

129 and C57BL/6 are two of the most widely used laboratory mouse strains. While it is well known that genetic modifiers between the two strains can directly influence embryonic and adult phenotypes, less is known regarding morphological differences in placental development. Here we identify differences in the junctional zone, glycogen storage and the maternal-fetal interface between these two strains and provide examples where these differences impact the phenotypic characterisation of placental mutations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Female
  • Glycogen / metabolism*
  • Mice
  • Mice, 129 Strain
  • Mice, Inbred C57BL
  • Placenta / metabolism*
  • Pregnancy
  • Species Specificity

Substances

  • Glycogen