Exercise-associated numbness and tingling in the legs

Arch Neurol. 2011 Dec;68(12):1599-602. doi: 10.1001/archneurol.2011.1195.


A 52-year-old physically active man with a medical history of coronary artery disease, hypertension, and hyperlipidemia presented with numbness and tingling in the legs. His symptoms were intermittent initially, triggered by running or playing soccer and relieved by rest. Symptoms progressed during 1 year. The numbness became more constant, and he developed leg pain radiating from the popliteal fossa to the heel bilaterally (pain was more severe in the left leg compared with the right leg). Recently, he had noted some constipation as well as difficulty in initiating urination.

Publication types

  • Case Reports
  • Clinical Conference

MeSH terms

  • Arteriovenous Fistula / complications*
  • Arteriovenous Fistula / diagnosis*
  • Disease Progression
  • Exercise / physiology
  • Humans
  • Hypesthesia / etiology
  • Male
  • Middle Aged
  • Running / physiology
  • Spinal Cord Diseases / complications*
  • Spinal Cord Diseases / diagnosis*