Using the scan-x Web site to predict protein post-translational modifications

Curr Protoc Bioinformatics. 2011 Dec;Chapter 13:Unit 13.16.. doi: 10.1002/0471250953.bi1316s36.

Abstract

The recent plethora of proteomic mass spectrometry data is providing evidence that almost every protein in the cell undergoes some form of post-translational modification. We describe a protocol to use the scan-x Web site to view predicted acetylation sites in the human proteome and predicted phosphorylation sites in the human, mouse, fly, and yeast proteomes with high specificity. This tool is accessible from virtually any computer with a Web browser. The only requirement is a means of searching for a protein of interest in one of the represented organisms.

MeSH terms

  • Acetylation
  • Animals
  • Diptera
  • Fungal Proteins / chemistry
  • Fungal Proteins / metabolism
  • Humans
  • Insect Proteins / chemistry
  • Insect Proteins / metabolism
  • Internet
  • Methylation
  • Mice
  • Phosphorylation
  • Protein Processing, Post-Translational
  • Proteins / chemistry
  • Proteins / metabolism*
  • Proteome / analysis*
  • Proteome / chemistry
  • Proteomics
  • Saccharomyces
  • Software*

Substances

  • Fungal Proteins
  • Insect Proteins
  • Proteins
  • Proteome