Abstract
Six new triterpenoids including four new secodammarane triterpenoid glycosides (1-4), an epoxydammarane triterpenoid glycoside (5), and a new secodammarane triterpenoid (6) were isolated from the ethanolic extract of the leaves of Cyclocarya paliurus. The structures of these compounds were elucidated by spectroscopic analysis methods. Compounds 1-6 were evaluated for their inhibitory activities against α-glucosidase, lipase, DPP-IV, and aldose reductase.
© Georg Thieme Verlag KG Stuttgart · New York.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aldehyde Reductase / antagonists & inhibitors
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Aldehyde Reductase / metabolism
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China
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Enzyme Inhibitors / isolation & purification
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Enzyme Inhibitors / pharmacology
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Glycoside Hydrolase Inhibitors
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Glycosides / isolation & purification
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Glycosides / pharmacology
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Juglandaceae / chemistry*
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Lipase / antagonists & inhibitors
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Lipase / metabolism
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Plant Extracts / isolation & purification
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Plant Extracts / pharmacology
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Plant Leaves / chemistry
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Triterpenes / isolation & purification*
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Triterpenes / pharmacology*
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alpha-Glucosidases / metabolism
Substances
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Enzyme Inhibitors
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Glycoside Hydrolase Inhibitors
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Glycosides
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Plant Extracts
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Triterpenes
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Aldehyde Reductase
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Lipase
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alpha-Glucosidases