Optimal reperfusion in ST-elevation myocardial infarction--the role of the coronary microcirculation

Swiss Med Wkly. 2011 Dec 9;141:w13313. doi: 10.4414/smw.2011.13313. eCollection 2011.


Coronary microcirculation plays a crucial role for the outcomes of patients with STEMI. Although PPCI improves outcomes compared to thrombolysis, a substantial amount of STEMI patients do not achieve optimal myocardial reperfusion. Angiographic methods for assessment of reperfusion like TIMI Flow and MBG are easy to use but new, catheter laboratory based techniques to assess reperfusion have a lot of potential to assess and potentially guide management of patients with STEMI.

Publication types

  • Review

MeSH terms

  • Coronary Circulation / physiology*
  • Heart / physiology*
  • Humans
  • Microcirculation / physiology*
  • Myocardial Infarction / physiopathology*
  • Myocardial Infarction / therapy
  • Myocardial Reperfusion / methods*