Severe infection in a lung transplant recipient caused by donor-transmitted carbapenem-resistant Acinetobacter baumannii

Transpl Infect Dis. 2012 Jun;14(3):316-20. doi: 10.1111/j.1399-3062.2011.00701.x. Epub 2011 Dec 14.

Abstract

We describe a case of proven donor transmission of carbapenem-resistant Acinetobacter baumannii, which resulted in severe infectious complications after lung transplantation. A single bla(OXA-23) positive strain, belonging to a new multilocus sequence type (ST231), was isolated from donor and recipient, who died 65 days after transplantation. This report highlights the current challenges associated with the potential transmission of multidrug-resistant infections through organ transplantation.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter Infections / diagnosis
  • Acinetobacter Infections / drug therapy
  • Acinetobacter Infections / transmission*
  • Acinetobacter baumannii / drug effects
  • Acinetobacter baumannii / isolation & purification*
  • Bacteremia / diagnosis
  • Bacteremia / drug therapy
  • Bacteremia / microbiology*
  • Carbapenems / therapeutic use*
  • Fatal Outcome
  • Female
  • Humans
  • Lung Transplantation / adverse effects*
  • Middle Aged
  • Time Factors
  • Tissue Donors*
  • beta-Lactam Resistance*

Substances

  • Carbapenems