Application of cultured human regulatory T cells requires preclinical in vivo evaluation

J Allergy Clin Immunol. 2012 Mar;129(3):852-855.e3. doi: 10.1016/j.jaci.2011.10.037. Epub 2011 Dec 9.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biomarkers / metabolism
  • Biotechnology / methods
  • CD4 Antigens / metabolism
  • CTLA-4 Antigen / genetics
  • CTLA-4 Antigen / immunology
  • CTLA-4 Antigen / metabolism*
  • Cell Proliferation
  • Cells, Cultured
  • Forkhead Transcription Factors / genetics
  • Forkhead Transcription Factors / immunology
  • Forkhead Transcription Factors / metabolism*
  • Glucocorticoid-Induced TNFR-Related Protein / genetics
  • Glucocorticoid-Induced TNFR-Related Protein / immunology
  • Glucocorticoid-Induced TNFR-Related Protein / metabolism
  • Humans
  • Immunosuppression
  • Immunotherapy, Adoptive*
  • Interleukin-2 Receptor alpha Subunit / metabolism
  • Mice
  • Mice, SCID
  • T-Lymphocyte Subsets / immunology
  • T-Lymphocyte Subsets / pathology
  • T-Lymphocyte Subsets / transplantation*
  • T-Lymphocytes, Regulatory / immunology
  • T-Lymphocytes, Regulatory / pathology
  • T-Lymphocytes, Regulatory / transplantation*

Substances

  • Biomarkers
  • CD4 Antigens
  • CTLA-4 Antigen
  • CTLA4 protein, human
  • FOXP3 protein, human
  • Forkhead Transcription Factors
  • Glucocorticoid-Induced TNFR-Related Protein
  • Interleukin-2 Receptor alpha Subunit
  • TNFRSF18 protein, human